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Causality matters in medical imaging

Daniel C. Castro, Ian Walker, Ben Glocker

2020Nature Communications312 citationsDOIOpen Access PDF

Abstract

Causal reasoning can shed new light on the major challenges in machine learning for medical imaging: scarcity of high-quality annotated data and mismatch between the development dataset and the target environment. A causal perspective on these issues allows decisions about data collection, annotation, preprocessing, and learning strategies to be made and scrutinized more transparently, while providing a detailed categorisation of potential biases and mitigation techniques. Along with worked clinical examples, we highlight the importance of establishing the causal relationship between images and their annotations, and offer step-by-step recommendations for future studies.

Topics & Concepts

Causality (physics)Perspective (graphical)Data scienceScarcityComputer scienceMedical imagingArtificial intelligenceMachine learningCausal inferenceCausal modelMEDLINERisk analysis (engineering)Medical researchManagement sciencePsychologyPrecision medicineMedical decision makingCognitive psychologyExplainable Artificial Intelligence (XAI)Artificial Intelligence in Healthcare and EducationMachine Learning in Healthcare
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