Phthalide derivative CD21 regulates the platelet- neutrophil extracellular trap-thrombin axis and protects against ischemic brain injury in rodents
Meiling Wu, Xiao Zou, Xiaoyu Chen, Kai-Ting Ma, Chu Chen, Nengwei Yu, Lu Yu, Junrong Du
Topics & Concepts
MyeloperoxidaseNeutrophil extracellular trapsPharmacologyProinflammatory cytokineChemistryNeutrophil elastaseIschemiaBrain ischemiaMedicineThrombinPlateletEndocrinologyInternal medicineInflammationNeutrophil, Myeloperoxidase and Oxidative MechanismsNeuroinflammation and Neurodegeneration MechanismsS100 Proteins and Annexins