LuxS/AI-2 Quorum Sensing System in Edwardsiella piscicida Promotes Biofilm Formation and Pathogenicity
Yongcan Sun, Yu Li, Qian Luo, Jinjing Huang, Jiakang Chen, Ruiqing Zhang, Xuepeng Wang
Abstract
LuxS/AI-2 is an important quorum sensing system which affects the growth, biofilm formation, virulence, and metabolism of bacteria. LuxS is encoded by the luxS gene, but how this gene is associated with a diverse array of physiological activities in Edwardsiella piscicida ( E. piscicida ) is not known. Here, we constructed an luxS gene mutant strain, the △ luxS strain, to identify how LuxS/AI-2 affects pathogenicity.
Topics & Concepts
BiofilmQuorum sensingBiologyMicrobiologyVirulenceComplementationMutantGeneBacteriaGeneticsBacterial biofilms and quorum sensingLegionella and Acanthamoeba researchWater Treatment and Disinfection