Orthopedic Implant-Related Biofilm Pathophysiology: A Review of the Literature
Meletis Rozis, Dimitrios Stergios Evangelopoulos, Spyros G Pneumaticos
Abstract
Orthopedic implant-related infections remain a major problem even nowadays. Bacterial resistance through biofilm formation, in addition to the limited treatment options available, has resulted in an increased effort to better understand pathophysiology mechanisms. We performed a review of the literature in order to identify major biofilm formation pathways through which possible treatment strategies could arise.
Topics & Concepts
Orthopedic surgeryBiofilmPathophysiologyMedicineImplantSurgeryPathologyBiologyBacteriaGeneticsOrthopedic Infections and TreatmentsBacterial biofilms and quorum sensingOrthopaedic implants and arthroplasty