Litcius/Paper detail

Photoswitching of Diazocines in Aqueous Media

Pascal Lentes, Philipp Frühwirt, Hilde Freißmuth, Widukind Moormann, Fabian Kruse, Georg Gescheidt, Rainer Herges

2021The Journal of Organic Chemistry36 citationsDOI

Abstract

We present a systematic investigation of the photophysical properties of diazocines in aqueous media. The Z – E photoconversion yields of CH 2 CH 2 - and CH 2 S-bridged diazocines decrease with increasing water content in acetonitrile. However, there is one exception. A CH 2 -NAc-bridged diazocine mostly retains its photostationary state in water (85 to 72%) because of the high quantum yields for the Z → E conversion. Moreover, it is water-soluble without further substitution and is therefore ideally suited as a photoswitch in biological (aqueous) environments.

Topics & Concepts

Aqueous solutionAcetonitrileAqueous mediumPhotostationary stateChemistryPhotoswitchPhotochemistryCombinatorial chemistryOrganic chemistryCatalysisPhotoisomerizationIsomerizationPhotochromic and Fluorescence ChemistryPhotoreceptor and optogenetics researchPorphyrin and Phthalocyanine Chemistry