Interplay between Sulfur Assimilation and Biodesulfurization Activity in Rhodococcus qingshengii IGTS8: Insights into a Regulatory Role of the Reverse Transsulfuration Pathway
Όλγα Μαρτζούκου, Panayiotis D. Glekas, Margaritis Avgeris, Diomi Mamma, Andreas Scorilas, Dimitris Kekos, Sotiris Amillis, Dimitris G. Hatzinikolaou
Abstract
gene expression and biocatalyst activity, depending on the presence of two reverse transsulfuration enzymes, CβS and MetB. Moreover, we observed an enhancement of biodesulfurization capability in the presence of otherwise repressive sulfur sources, such as sulfate and l-methionine. The interconnection of cellular sulfur assimilation strategies was revealed and validated.
Topics & Concepts
TranssulfurationRhodococcusBiocatalysisChemistryAssimilation (phonology)GeneEnzymeComputational biologyBiochemistryCystathionine beta synthaseBiologyCatalysisReaction mechanismCysteinePhilosophyLinguisticsMicrobial Metabolic Engineering and BioproductionEnzyme Catalysis and ImmobilizationMetalloenzymes and iron-sulfur proteins