Targeting oxidative stress with amobarbital to prevent intervertebral disc degeneration: Part I. in vitro and ex vivo studies
Dongrim Seol, Mitchell C. Coleman, James A. Martin, Ino Song, L.R. Jaidev, Aliasger K. Salem, Tae‐Hong Lim
Topics & Concepts
Oxidative stressReactive oxygen speciesMedicineCell biologyEx vivop38 mitogen-activated protein kinasesPropidium iodideMitochondrionApoptosisAnnexinKinasePharmacologyPathologyMAPK/ERK pathwayProgrammed cell deathBiochemistryChemistryIn vitroBiologyInternal medicineStainingSpine and Intervertebral Disc PathologyCervical and Thoracic MyelopathySpondyloarthritis Studies and Treatments