<i>Akkermansia muciniphila</i> inhibits tryptophan metabolism via the AhR/β-catenin signaling pathway to counter the progression of colorectal cancer
Lu Zhang, Qing Ji, Qian Chen, Zhenzhen Wei, Shuochuan Liu, Long Zhang, Yuli Zhang, Zan Li, Huaimin Liu, Hua Sui
Abstract
. protected mice from CRC development by specifically inhibiting tryptophan-mediated AhR/β-catenin signaling.
Topics & Concepts
Akkermansia muciniphilaColorectal cancerAzoxymethaneCancer researchWnt signaling pathwayAryl hydrocarbon receptorBiologyCancerMedicineInternal medicineSignal transductionImmunologyGut floraTranscription factorCell biologyBiochemistryGeneGut microbiota and healthEpigenetics and DNA MethylationImmune cells in cancer