Human and Porcine Transmission of <i>Clostridioides difficile</i> Ribotype 078, Europe
Geraldine Moloney, David W. Eyre, Micheál Mac Aogáin, M. McElroy, Alison Vaughan, Tim Peto, Derrick W. Crook, Thomas R. Rogers
Abstract
C lostridioides (formerly Clostridium) diffi cile was considered to be a predominantly nosocomial pathogen until fi ndings of several whole-genome sequencing studies suggested a more complex epidemiology. For example, Eyre et al. reported that only 35% of nosocomial C. diffi cile infections (CDIs) were potentially attributable to other cases on the basis of genomic data, and only 19% were additionally linked through sharing possible hospital-based contact (1). This fi nding suggests that a major proportion of C. diffi cile from CDI cases occurring in healthcare institutions originates from other sources, including the community (2).