Au nanocluster-modulated macrophage polarization and synoviocyte apoptosis for enhanced rheumatoid arthritis treatment
Hao Chen, Yongxin Jiang, Tingting Xu, Jiangmei Xu, Jun Yu, Zhaoyou Chu, Yechun Jiang, Yongbo Song, Hua Wang, Haisheng Qian
Abstract
nanoclusters efficiently ameliorated the hyperplasia of the synovium and reduced inflammatory cell infiltration with negligible side effects. This study provided a new insight into Au nanoclusters for treating rheumatoid arthritis.
Topics & Concepts
Thioredoxin reductaseApoptosisNanoclustersMacrophage polarizationRheumatoid arthritisMacrophageCancer researchPolarization (electrochemistry)Materials scienceCell biologyChemistryThioredoxinMedicineImmunologyNanotechnologyBiochemistryBiologyEnzymeIn vitroPhysical chemistryNanocluster Synthesis and ApplicationsAdvanced Nanomaterials in CatalysisAlzheimer's disease research and treatments