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Multicomponent Reaction of Isocyanide, Ditelluride, and Mn(III) Carboxylate: Synthesis of <i>N</i>-Acyl Tellurocarbamate

Jianjian Zha, Zhuoer Wang, Bingxin Liu, Qitao Tan, Bin Xu

2022Organic Letters12 citationsDOI

Abstract

A multicomponent reaction of isocyanides, ditellurides and manganese(III) carboxylates under mild reaction conditions leads to the synthesis of various N-acyl tellurocarbamates. This method demonstrates good functional tolerance and broad substrate scope and, as a result, is especially suitable for the postfunctionalization of complicated molecules such as drugs. The given method can be further extended to the synthesis of selenocarbamates.

Topics & Concepts

ChemistryIsocyanideCarboxylateManganeseSubstrate (aquarium)Combinatorial chemistryMoleculeScope (computer science)Reaction conditionsStereochemistryOrganic chemistryCatalysisComputer scienceGeologyOceanographyProgramming languageOrganoselenium and organotellurium chemistrySulfur-Based Synthesis TechniquesChemical Synthesis and Reactions
Multicomponent Reaction of Isocyanide, Ditelluride, and Mn(III) Carboxylate: Synthesis of <i>N</i>-Acyl Tellurocarbamate | Litcius