Electrochemical Oxidative C–H Thiocyanation or Selenocyanation of Imidazopyridines and Arenes
Ping Liu, Peipei Sun, Ting Cui, Xiaofeng Zhang, Jun Lin, Zitong Zhu
Abstract
Regioselective electrochemical oxidative C–H thiocyanation or selenocyanation of imidazopyridines was achieved by using an undivided electrolytic cell. Transition-metal- and oxidant-free conditions are striking features of this protocol. A library of thiocyanated imidazopyridines with a broad range of functional groups were synthesized in high yields. This method was also applicable to the thiocyanation or selenocyanation of some electron-rich arenes.
Topics & Concepts
ChemistryRegioselectivityElectrochemistryOxidative phosphorylationCombinatorial chemistryOrganic chemistryCatalysisElectrodeBiochemistryPhysical chemistrySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization MethodsRadical Photochemical Reactions