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An electrochemical ratiometric biosensor for the detection of dopamine based on an MXene-Au nanocomposite

Wenjie Jing, Feifei Li, Yu Liu, Rong-Na Ma, Wei Zhang, Lei Shang, Xiaojian Li, Qingwang Xue, Huaisheng Wang, Liping Jia

2023Chemical Communications22 citationsDOI

Abstract

Compared with single signal detection, a ratiometric biosensor could offer more accurate and reliable results. Here, a ratiometric electrochemical biosensor for the sensitive and accurate detection of dopamine was developed based on the strong adsorption ability of MXene-Au toward methylene blue, an inner reference element. This ratiometric sensing strategy opened up a new avenue for the development of a ratiometric platform.

Topics & Concepts

BiosensorMethylene blueNanocompositeElectrochemistryAdsorptionNanotechnologyDopamineChemistryMaterials scienceElectrodeOrganic chemistryPhysical chemistryPhotocatalysisCatalysisNeuroscienceBiologyMXene and MAX Phase MaterialsAdvanced biosensing and bioanalysis techniques2D Materials and Applications
An electrochemical ratiometric biosensor for the detection of dopamine based on an MXene-Au nanocomposite | Litcius