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SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

Jitske Jansen, Katharina C. Reimer, James S. Nagai, Finny S. Varghese, Gijs J. Overheul, Marit de Beer, Rona Roverts, Deniz Daviran, Liline A.S. Fermin, Brigith Willemsen, Marcel Beukenboom, Sonja Djudjaj, Saskia von Stillfried, Larissa E. van Eijk, Mirjam F. Mastik, Marian Bulthuis, Wilfred F.A. den Dunnen, Harry van Goor, Jan‐Luuk Hillebrands, Sergio Triana, Theodore Alexandrov, M. Cherelle Timm, Bartholomeus T. van den Berge, Martijn van den Broek, Quincy Nlandu, Joelle Heijnert, Eric M. Bindels, Remco M. Hoogenboezem, Fieke Mooren, Christoph Kuppe, Pascal Miesen, Katrien Grünberg, Ties Ijzermans, Eric J. Steenbergen, Jan Czogalla, Michiel F. Schreuder, Nico A. J. M. Sommerdijk, Anat Akiva, Peter Boor, Victor G. Puelles, Jürgen Floege, Tobias B. Huber, Hagit Achdout, A. Aimon, Elad Bar-David, Haim Barr, Amir Ben‐Shmuel, James M. Bennett, Melissa L. Boby, Bruce Borden, Gregory R. Bowman, Juliane Brun, Sarma BVNBS, Mark Calmiano, Anna Carbery, Emma Cattermole, Eugene Chernychenko, John D. Choder, Austin Clyde, Joseph E. Coffland, Galit Cohen, Jason C. Cole, Alessandro Contini, Lisa Sanderson Cox, Milan Cvitkovic, Alex Dias, Kim Donckers, David Dotson, Alica Douangamath, Shirly Duberstein, Tim Dudgeon, Louise Dunnett, Peter Eastman, Noam Erez, Charles J. Eyermann, Mike Fairhead, Gwen Fate, D. Fearon, Oleg Federov, Matteo P. Ferla, R.S. Fernandes, Lori Ferrins, Richard Foster, Holly Foster, Ronen Gabizon, Adolfo García‐Sastre, Victor O. Gawriljuk, Paul Gehrtz, C. Gileadi, Charline Giroud, William G. Glass, Robert C. Glen, Itai glinert, André S. Godoy, Marian V. Gorichko, T.J. Gorrie-Stone, Ed Griffen, Storm Hassell Hart, Jag Heer, Micheal Henry

2021Cell stem cell266 citationsDOIOpen Access PDF

Topics & Concepts

KidneyBiologyInduced pluripotent stem cellAcute kidney injuryFibrosisOrganoidVirologyKidney diseaseVirusImmunologyCancer researchPathologyCell biologyInternal medicineMedicineEndocrinologyGeneEmbryonic stem cellGeneticsCOVID-19 and healthcare impactsRenal and related cancersChronic Kidney Disease and Diabetes
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids | Litcius