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A field guide to flow chemistry for synthetic organic chemists

Luca Capaldo, Zhenghui Wen, Timothy Noël

2023Chemical Science367 citationsDOIOpen Access PDF

Abstract

Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious "black box" needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By "lifting the veil" on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry.

Topics & Concepts

Flow chemistryOrganic synthesisContinuous flowField (mathematics)ChemistryBiochemical engineeringNanotechnologyPolymer scienceOrganic chemistryEngineeringMaterials scienceMathematicsCatalysisPure mathematicsInnovative Microfluidic and Catalytic Techniques InnovationMicrofluidic and Capillary Electrophoresis ApplicationsOxidative Organic Chemistry Reactions
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