Molecular engineering of complexation between RNA and biodegradable cationic gemini surfactants: role of the hydrophobic chain length
Mohd. Akram, Hira Lal, Sonam Shakya, Rohit Varshney, KABIR‐UD‐DIN KABIR‐UD‐DIN
Abstract
The effects of the hydrophobic alkyl chain length of C m -E2O-C m gemini surfactants ( m = 12, 14 and 16) on ribonucleic acid were investigated using different methods. The various calculated parameters revealed that complexation occurs via an intercalative binding mode.
Topics & Concepts
Cationic polymerizationAlkylChemistryChain (unit)RNAHydrophobic effectPolymer chemistryStereochemistryChemical engineeringOrganic chemistryBiochemistryPhysicsGeneAstronomyEngineeringSurfactants and Colloidal SystemsProtein Interaction Studies and Fluorescence AnalysisDNA and Nucleic Acid Chemistry