Litcius/Paper detail

Stability and bifurcation analysis of a fractional-order single-gene regulatory model with delays under a novel PDα control law

Lu Qiu, Min Xiao, Zunshui Cheng, Yurong Song, Chengdai Huang, Jinde Cao

2020International Journal of Biomathematics16 citationsDOI

Abstract

In this paper, we propose a novel fractional-order proportional-derivative (PD) strategy to achieve the control of bifurcation of a fractional-order gene regulatory model with delays. The stability theory of fractional differential equations proved that with delays, some explicit conditions for the local asymptotical stability and Hopf bifurcation are given for the controlled fractional-order genetic model. It is demonstrated that the fractional-order gene regulatory model becomes controllable by adjusting the control gain parameters. In addition, the effect of fractional-order parameter on the dynamical behaviors is shown. Finally, numerical simulations are carried out to testify the validity of the main results and the availability of the fractional-order PD controller.

Topics & Concepts

Fractional calculusMathematicsBifurcationStability (learning theory)Control theory (sociology)Order (exchange)Hopf bifurcationController (irrigation)Applied mathematicsMathematical analysisControl (management)Nonlinear systemComputer sciencePhysicsEconomicsFinanceBiologyAgronomyMachine learningQuantum mechanicsArtificial intelligenceGene Regulatory Network AnalysisEvolution and Genetic DynamicsReceptor Mechanisms and Signaling