Synthesis and DNA interaction studies of Ru(<scp>ii</scp>) cell penetrating peptide (CPP) bioconjugates
Daniel Obitz, Reece G. Miller, Nils Metzler‐Nolte
Abstract
The synthesis and biological investigations of the first bioconjugates of ruthenium( ii ) dipyridophenazine complexes with two different covalently attached cell penetrating peptides (CPPs) is described.
Topics & Concepts
PeptideChemistryRutheniumCovalent bondCell-penetrating peptideDNACombinatorial chemistryBiochemistryStereochemistryOrganic chemistryCatalysisRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid Chemistry