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HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis

Sally A. Abuelezz, Nevien Hendawy

2021Life Sciences49 citationsDOI

Topics & Concepts

PCSK9CholesterolEndocrinologyInternal medicineTREM2NeurodegenerationKexinLiver X receptorLDL receptorGlycationMedicineChemistryInflammationReceptorLipoproteinBiochemistryMicrogliaNuclear receptorGeneDiseaseTranscription factorAdvanced Glycation End Products researchAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms
HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis | Litcius