A Click Synthesis, Molecular Docking and Biological Evaluation of 1,2,3-triazoles-benzoxazepine hybrid as potential anticancer agents
Muhammad Ashram, Almeqdad Y. Habashneh, Sanaa K. Bardaweel, Mutasem O. Taha
Topics & Concepts
PharmacophoreChemistryIn silicoClick chemistryDocking (animal)1,2,3-TriazoleIn vitroCytotoxicityHL60StereochemistryIC50Combinatorial chemistryTriazoleCancer cellCancer cell linesBiochemistryCancerOrganic chemistryBiologyNursingGeneticsMedicineGeneClick Chemistry and ApplicationsSynthesis and biological activityCancer therapeutics and mechanisms