Organoid biobanks as a new tool for pre-clinical validation of candidate drug efficacy and safety.
Gerardo Botti, Maurizio Di Bonito, Monica Cantile
Abstract
The growing need for personalized medicine for cancer patients has enhanced and optimized the production of living tumor organoids that have become optimal preclinical models for the discovery and screening of anticancer drugs. The systematic collection and storage of tumor organoids through the establishment of dedicated biobanks will represent a fundamental tool for cancer research and clinical trials.
Topics & Concepts
BiobankOrganoidClinical trialPersonalized medicineDrug discoveryMedicineDrugPrecision medicineComputational biologyPharmacologyBioinformaticsComputer scienceOncologyInternal medicineBiologyPathologyNeuroscienceCancer Genomics and DiagnosticsCancer Cells and MetastasisPharmacogenetics and Drug Metabolism