Litcius/Paper detail

Removing non-resonant background from broadband CARS using a physics-informed neural network

Ryan Muddiman, Kevin O’Dwyer, Charles H. Camp, Bryan M. Hennelly

2023Analytical Methods19 citationsDOIOpen Access PDF

Abstract

, with millisecond acquisition times. Raw BCARS spectra, however, are a coherent combination of vibrationally resonant (Raman) and non-resonant (electronic) components that may challenge or degrade chemical analyses. Recently, we demonstrated a deep convolutional autoencoder network, trained on pairs of simulated BCARS-Raman datasets, which could retrieve the Raman signal with high quality under ideal conditions. In this work, we present a new computational system that incorporates experimental measurements of the laser system spectral and temporal properties, combined with simulated susceptibilities. Thus, the neural network learns the mapping between the susceptibility and the measured response for a specific BCARS system. The network is tested on simulated and measured experimental results taken with our BCARS system.

Topics & Concepts

Raman spectroscopyRaman scatteringBroadbandAutoencoderArtificial neural networkConvolutional neural networkCoherent anti-Stokes Raman spectroscopySIGNAL (programming language)Computer scienceLaserExcitationSpectral linePhysicsMaterials scienceArtificial intelligenceOpticsQuantum mechanicsAstronomyProgramming languageSpectroscopy Techniques in Biomedical and Chemical ResearchSpectroscopy and Chemometric AnalysesListeria monocytogenes in Food Safety