Marine paralytic shellfish toxins: chemical properties, mode of action, newer analogues, and structure–toxicity relationship
Joana F. Leal, Maria L. S. Cristiano
Abstract
, effect of the substituting groups and the net charge of the molecules) and the toxic activity of these molecules is performed, proposing the concept of "toxicological traffic light" based on the toxicity equivalency factors (TEFs).
Topics & Concepts
Mode of actionMarine toxinShellfishShellfish poisoningToxicityChemistryComputational biologyBiologyToxicologyFisheryToxinBiochemistryFish <Actinopterygii>Aquatic animalOrganic chemistryMarine Toxins and Detection MethodsNicotinic Acetylcholine Receptors StudyMarine Invertebrate Physiology and Ecology