The role of hepatic cytochrome P450s in the cytotoxicity of sertraline
Si Chen, Qiangen Wu, Xilin Li, Dongying Li, Michelle Fan, Zhen Ren, Matthew Bryant, Nan Mei, Baitang Ning, Lei Guo
Topics & Concepts
SertralineCytotoxicityTopoisomerasePharmacologyCytochrome P450CYP2D6FluoxetineChemistryBiologyMedicineAntidepressantBiochemistryMetabolismIn vitroPsychiatryReceptorAnxietySerotoninPharmacogenetics and Drug MetabolismCancer therapeutics and mechanismsDrug-Induced Hepatotoxicity and Protection