METTL3 Induces AAA Development and Progression by Modulating N6-Methyladenosine-Dependent Primary miR34a Processing
Lintao Zhong, Xiang He, Haoyu Song, Yili Sun, Guojun Chen, Xiaoyun Si, Jie Sun, Xiaoqiang Chen, Wangjun Liao, Yulin Liao, Jianping Bin
Abstract
A-mediated miR-34a maturation in AAA formation and provide a novel therapeutic target and diagnostic biomarker for AAA treatment.
Topics & Concepts
Gene knockdownAbdominal aortic aneurysmmicroRNAAngiotensin IICancer researchMedicineApolipoprotein ECell biologyChemistryInternal medicineBiologyReceptorAneurysmSurgeryBiochemistryGeneDiseaseRNA modifications and cancerHybrid Renewable Energy SystemsAortic aneurysm repair treatments