Litcius/Paper detail

Dietary Selenium deficiency activates the NLRP3 inflammasome to induce gallbladder pyroptosis by regulating glycolysis and histone lactylation through ROS/HIF-1α pathway

Zhengzhe An, Haodong Hu, Qian Wang, Yaning Qiu, Jiahong Chu, Yu Xia, Shu Li

2025The Journal of Nutritional Biochemistry10 citationsDOI

Topics & Concepts

PyroptosisGlycolysisInflammasomeHistoneSelenium deficiencyOxidative stressCell biologyAnaerobic glycolysisInflammationOxidative phosphorylationChemistryBiologyReactive oxygen speciesAutophagyCancer researchHistone H3Metabolic pathwayBiochemistryEpigeneticsGene knockdownHomeostasisProgrammed cell deathAcetylationWarburg effectPyrin domainInflammasome and immune disordersSelenium in Biological SystemsGout, Hyperuricemia, Uric Acid