Resveratrol-loaded biopolymer core–shell nanoparticles: bioavailability and anti-inflammatory effects
Ye Liu, Xiao Liang, Yan Zou, Yaqi Peng, David Julian McClements, Kun Hu
Abstract
, IL-1β, IL-6, TNF-α, promoting IL-10 release, inhibiting expression of TLR4, and inhibiting phosphorylation of JNK, ERK1/2, p38 and MAPK. Overall, this research suggests that zein-pectin core/shell nanoparticles are a highly effective delivery system for resveratrol, significantly increasing its bioavailability and anti-inflammation activity. These oral delivery systems may be particularly suitable for applications in functional foods or pharmaceuticals.
Topics & Concepts
ResveratrolChemistryBioavailabilityPharmacologyOral administrationLipopolysaccharideBiochemistryEndocrinologyMedicineElectrospun Nanofibers in Biomedical ApplicationsFood and Agricultural SciencesMicroencapsulation and Drying Processes