Back Cover: An Enzymatically Gated Catalytic Hairpin Assembly Delivered by Lipid Nanoparticles for the Tumor‐Specific Activation of Signal Amplification in miRNA Imaging (Angew. Chem. Int. Ed. 51/2022)
Qing Liu, Yuanyu Huang, Zhengping Li, Lele Li, Yuliang Zhao, Mengyuan Li
Abstract
Tumor-specific miRNA imaging is achieved through the integration of enzyme-triggered catalytic hairpin assembly with lipid-nanoparticle-based delivery. The approach enables controlled activation of signal amplification in cancer cells with improved imaging contrast, as reported by Lele Li, Mengyuan Li, and co-workers in their Research Article (e202214230).
Topics & Concepts
microRNANanoparticleChemistryBiophysicsSIGNAL (programming language)EnzymeNanotechnologyMaterials scienceBiochemistryBiologyComputer scienceGeneProgramming languageRNA Interference and Gene DeliveryClick Chemistry and ApplicationsAdvanced biosensing and bioanalysis techniques