Safflospermidines from the bee pollen of Helianthus annuus L. exhibit a higher in vitro antityrosinase activity than kojic acid
Phanthiwa Khongkarat, Rico Ramadhan, Preecha Phuwapraisirisan, Chanpen Chanchao
Abstract
BACKGROUND: L.) was evaluated. MATERIALS AND METHODS: CC) and high performance liquid chromatography (HPLC), and their chemical structure deduced by Nuclear Magnetic Resonance (NMR) analysis. RESULTS: of 44.0 μM). However, fraction DCMSBP5 had no significant antioxidation activity, while fractions DCMSBP1-4 showed a lower antioxidation activity than ascorbic acid. CONCLUSION: Safflospermidine A and B are potential natural tyrosinase inhibitors.
Topics & Concepts
Column chromatographyDPPHChemistryMelaninIC50High-performance liquid chromatographyTyrosinaseHelianthus annuusTraditional medicineSunflowerChromatographyBotanyAntioxidantBiochemistryIn vitroBiologyMedicineHorticultureEnzymemelanin and skin pigmentationBee Products Chemical AnalysisInsect and Pesticide Research