Crystal structure of tubulin-barbigerone complex enables rational design of potent anticancer agents with isoflavone skeleton
Wei Yan, Yong Li, Yan Liu, Yi Wen, Heying Pei, Jianhong Yang, Lijuan Chen
Topics & Concepts
TubulinMicrotubuleHeLaChemistryIn vitroColchicineBiochemistryCell biologyBiologyGeneticsBioactive natural compoundsSynthesis and biological activitySynthesis of Organic Compounds