Deciphering the AChE-binding mechanism with multifunctional tricyclic coumarin anti-Alzheimer's agents using biophysical and bioinformatics approaches and evaluation of their modulating effect on Amyloidogenic peptide assembly
Jeelan Basha Shaik, Yelamanda Rao Kandrakonda, Monika Kallubai, Navya Naidu Gajula, Shreya Dubey, Bindu Madhava Reddy Aramati, Rajagopal Subramanyam, Gangaiah Damu Amooru
Topics & Concepts
ChemistryThioflavinDocking (animal)BiophysicsPeptideCoumarinBinding siteCytotoxicityBiochemistryAlzheimer's diseaseIn vitroBiologyPathologyOrganic chemistryMedicineDiseaseNursingComputational Drug Discovery MethodsCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatments