<i>In silico</i> screening predicts common cold drug Dextromethorphan along with Prednisolone and Dexamethasone can be effective against novel Coronavirus disease (COVID-19)
Indrani Sarkar, Arnab Sen
Abstract
) with PDB ID 6LU7 as the target protein in this analysis. Molecular docking and dynamics study further revealed their synergistic effect against the COVID-19 protease protein.Communicated by Ramaswamy H. Sarma.
Topics & Concepts
Drug repositioningCoronavirusIn silicoDrugPharmacologyVirologyCoronavirus disease 2019 (COVID-19)MedicinePrednisoloneProteaseDextromethorphanInfectious disease (medical specialty)DiseaseComputational biologyBiologyInternal medicineEnzymeGeneBiochemistrySARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery MethodsDiverse Scientific Research Studies