Acute disseminated encephalomyelitis (ADEM) associated with COVID-19
Lawrence Langley, C Zeicu, Louise Whitton, Mathilde Pauls
Abstract
A 53-year-old man admitted to the critical care secondary to respiratory failure due to COVID-19 developed agitation and global hypotonia. Brain MRI revealed bilateral hyperintense lesions throughout the brain and cerebrospinal fluid identified oligoclonal bands. Intravenous high-dose glucocorticoids were administered followed by an oral tapering dose and the patient clinically improved. Acute disseminated encephalomyelitis should be considered in patients with COVID-19 who present with altered mentation and polyfocal neurological deficits.
Topics & Concepts
Acute disseminated encephalomyelitisMedicineCerebrospinal fluidCoronavirus disease 2019 (COVID-19)EncephalomyelitisHypotoniaNeurologyPediatricsAnesthesiaPathologyCentral nervous systemInternal medicineInfectious disease (medical specialty)DiseasePsychiatryLong-Term Effects of COVID-19Multiple Sclerosis Research StudiesInfectious Encephalopathies and Encephalitis