Violacein and its antifungal activity: comments and potentialities
Nelsón Durán, Guillermo R. Castro, Ricardo Wagner Portela, Wagner José Fávaro, M. Durán, Ljubica Tasić, Gerson Nakazato
Abstract
Violacein is an important natural antimicrobial pigment that is mainly produced by Chromobacterium violaceum and Janthinobacterium lividum. It presents a significant range of effects against phytopathogenic and human fungi, besides being featured as having low toxicity, and by its important ecological role in protecting amphibian species and applications in dyed medical fabric. The hypothesis about violacein's action mechanisms against mucormycosis (Rhizopus arrhizus) and candidiasis (Candida auris) is herein discussed based on data available in the scientific literature.
Topics & Concepts
Chromobacterium violaceumRhizopus arrhizusBiologyMicrobiologyAntimicrobialAntifungalCandida aurisBiofilmBacteriaQuorum sensingGeneticsLipaseEnzymeBiochemistryMicrobial Metabolism and ApplicationsMedicinal Plants and NeuroprotectionPhytochemistry and Bioactivity Studies