Comprehensive characterization of antral and pyloric contractions by high resolution manometry: applied physiology in suspected gastroparesis
Ting Zheng, Joelle BouSaba, Wassel Sannaa, Deborah J. Eckert, Duane D. Burton, Michael Camilleri
2022American Journal of Physiology-Gastrointestinal and Liver Physiology28 citationsDOIOpen Access PDF
Abstract
Current selection of different treatments for patients with gastroparesis is empiric or based on trial and error, though pyloric distensibility and diameter may predict response to pyloric interventions. High-resolution antropyloroduodenal manometry (HR-ADM) can characterize a variety of postprandial antral contractile and pyloric motility dysfunctions in patients with suspected gastroparesis. HR-ADM shows promise to provide guidance for selection and individualization of treatments such as prokinetic agents or pyloric interventions for patients with gastroparesis based on documented pathophysiology.
Topics & Concepts
PostprandialAntrumGastroparesisMedicineGastric emptyingInternal medicineGastroenterologyPylorusContraction (grammar)Pyloric AntrumMotilityHigh resolution manometryStomachCardiologyBiologyEsophagusInsulinGeneticsAchalasiaGastrointestinal motility and disordersCardiovascular Syncope and Autonomic DisordersGastroesophageal reflux and treatments