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Clinical Performance of the Standard Q COVID-19 Rapid Antigen Test and Simulation of its Real-World Application in Korea

Jaehyeon Lee, So Yeon Kim, Hee Jae Huh, Namsu Kim, Heungsup Sung, Hyukmin Lee, Kyoung Ho Roh, Taek Soo Kim, Ki Ho Hong

2021Annals of Laboratory Medicine30 citationsDOIOpen Access PDF

Abstract

) threshold cycle (Ct) values ≤23.37, which is the limit of detection of SQ-RAT. The specificity was 100%. The clinical sensitivity of SQ-RAT for COVID-19 diagnosis was assessed based on the Ct distribution at diagnosis of 33,294 COVID-19 cases in Korea extracted from the laboratory surveillance system of Korean Society for Laboratory Medicine. The clinical sensitivity of SQ-RAT for COVID-19 diagnosis in the Korean population was 41.8%. Considering the molecular testing capacity in Korea, use of the RAT for COVID-19 diagnosis appears to be limited.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Test (biology)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Computer scienceVirologyMedicineInternal medicineBiologyDiseasePaleontologyInfectious disease (medical specialty)SARS-CoV-2 detection and testingSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies