Bis-quaternary ammonium gemini surfactants for gene therapy: Effects of the spacer hydrophobicity on the DNA complexation and biological activity
Delvis Rafael Acosta-Martínez, Eustolia Rodríguez‐Velázquez, Fernanda Araiza-Verduzco, Pablo Taboada, Gerardo Prieto, Ignacio A. Rivero, Georgina Pina‐Luis, Manuel Alatorre‐Meda
Topics & Concepts
Isothermal titration calorimetryChemistryMicelleAlkylDynamic light scatteringCritical micelle concentrationHydrophobic effectDNAMonomerTitrationSide chainPolymer chemistryOrganic chemistryPolymerBiochemistryAqueous solutionNanotechnologyMaterials scienceNanoparticleRNA Interference and Gene DeliveryDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniques