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Fibromuscular Dysplasia: A Focused Review for the Cardiologist

Taylor Petropoulos, Anita Shah, Andrew Dueck, Christine Hawkes, Sheldon W. Tobe, William Kingston, Mina Madan

2024CJC Open14 citationsDOIOpen Access PDF

Abstract

Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndromes. Fibromuscular dysplasia (FMD) is an idiopathic, nonatherosclerotic, and noninflammatory arterial disease that affects small- to medium-sized arteries that can result in multifocal aneurysms, stenosis, tortuosity, and dissections. Extracoronary FMD has been identified in approximately 70% of SCAD patients and it is recommended that all SCAD patients undergo screening for FMD once in their lifetime using computed tomography angiography from head to pelvis. This focused review for cardiologists outlines current approaches to diagnosis and management of patients with FMD.

Topics & Concepts

Fibromuscular dysplasiaMedicineScadCardiologyTortuosityInternal medicineRadiologyArtery dissectionCoronary artery diseaseStenosisDissection (medical)Computed tomographic angiographyAngiographyCoronary angiographyRenal arteryMyocardial infarctionKidneyEngineeringPorosityGeotechnical engineeringCardiovascular Issues in PregnancyRenal and Vascular PathologiesNeurological Complications and Syndromes