Current Perspectives on the Management of Herpesvirus Infections in Solid Organ Transplant Recipients
S. Reshwan K. Malahe, Jeroen J. A. van Kampen, Olivier C. Manintveld, Rogier A.S. Hoek, Caroline M. den Hoed, Carla C. Baan, Marcia M. L. Kho, Georges M. G. M. Verjans
Abstract
Solid organ transplant recipients (SOTRs) are at high risk of human herpesvirus (HHV)-related morbidity and mortality due to the use of immunosuppressive therapy. We aim to increase awareness and understanding of HHV disease burden in SOTRs by providing an overview of current prevention and management strategies as described in the literature and guidelines. We discuss challenges in both prevention and treatment as well as future perspectives.
Topics & Concepts
Intensive care medicineMedicineOrgan transplantationDiseaseSolid organTransplantationImmunologyPathologyInternal medicineCytomegalovirus and herpesvirus researchHerpesvirus Infections and TreatmentsViral-associated cancers and disorders