Therapeutic effects of boronate ester cross-linked injectable hydrogels for the treatment of hepatocellular carcinoma
Jae Min Jung, Seong‐Han Kim, V.H. Giang Phan, Thavasyappan Thambi, Doo Sung Lee
Abstract
antitumor effect demonstrated that the DOX releasing hydrogel depot remarkably suppresses the tumor growth. These results demonstrate that the pH-responsive DOX releasing thermo-responsive hydrogel depot has great potential for application in localized anticancer therapy.
Topics & Concepts
ChemistryIn vivoConjugateEthylene glycolGlucuronic acidDoxorubicinCaprolactoneCopolymerHepatocellular carcinomaSelf-healing hydrogelsIn vitroPolymer chemistryBiophysicsCancer researchBiochemistryOrganic chemistryChemotherapySurgeryMedicinePolysaccharideMathematical analysisMathematicsPolymerBiotechnologyBiologyNanoparticle-Based Drug DeliveryHydrogels: synthesis, properties, applicationsSupramolecular Self-Assembly in Materials