SAMPL7 blind challenge: quantum–mechanical prediction of partition coefficients and acid dissociation constants for small drug-like molecules
Basak Koca Fındık, Zeynep Pinar Haslak, Evrim Arslan, Vi̇ktorya Avi̇yente
Topics & Concepts
SolvationMoleculeChemistryPartition coefficientOctanolComputational chemistryIsodesmic reactionQuantum chemicalQuantum chemistryQuantumThermodynamicsDissociation (chemistry)Quantitative structure–activity relationshipPhysical chemistryStereochemistryPhysicsOrganic chemistrySupramolecular chemistryQuantum mechanicsFree Radicals and AntioxidantsChemical Reaction MechanismsSpectroscopy and Quantum Chemical Studies