Photocytotoxicity and photoinduced phosphine ligand exchange in a Ru(<scp>ii</scp>) polypyridyl complex
Sean J. Steinke, Sayak Gupta, Eric J. Piechota, Curtis E. Moore, Jeremy J. Kodanko, Claudia Turró
Abstract
New Ru( ii ) complexes exhibit selective ligand dissociation driven by an excited state trans -type influence. The complexes are not toxic to triple-negative breast cancer cells in the dark, but induce cell death upon irradiation with visible light.
Topics & Concepts
PhosphineLigand (biochemistry)ChemistryPhotochemistryOrganic chemistryCatalysisBiochemistryReceptorLanthanide and Transition Metal ComplexesMetal complexes synthesis and propertiesPorphyrin and Phthalocyanine Chemistry