Litcius/Paper detail

Probiotics and autoprobiotics for treatment of <i>Helicobacter pylori</i> infection

Н. В. Барышникова, Anastasia S Ilina, Е. И. Ермоленко, Yury P. Uspenskiy, А. Н. Суворов

2023World Journal of Clinical Cases28 citationsDOIOpen Access PDF

Abstract

Inflammatory myofibroblastic tumor (IMT) of the biliary tract is rare, and often difficult to diagnose or to distinguish from other tumors due to its atypical clinical presentation and nonspecific radiological features. Histologically, IMTs are (myo)fibroblastic neoplasms with a prominent inflammatory infiltrate. They are characterized by receptor tyrosine kinase gene rearrangements, most often involving an anaplastic lymphoma kinase (ALK ) translocation. The final diagnosis of IMT depends on histopathology and immunohistochemical examination. In this manuscript, we provide a clinical and morphomolecular overview of IMT and the difficulties that may arise in using immunohistochemical and molecular techniques in diagnosing IMT.

Topics & Concepts

MedicineAnaplastic lymphoma kinaseHistopathologyImmunohistochemistryPathologyLymphomaHelicobacter pyloriGastrointestinal tractInternal medicineMalignant pleural effusionLung cancerHelicobacter pylori-related gastroenterology studiesNeuroendocrine Tumor Research AdvancesGastrointestinal disorders and treatments