Engineering of Saccharomyces pastorianus old yellow enzyme 1 for the synthesis of pharmacologically active (S)-profen derivatives
Guigao Liu, Li Shang, Qinghua Shi, Hengyu Li, Jiyang Guo, Jingping Ouyang, Xian Jia, Lihan Zhang, Song You, Bin Qin
Topics & Concepts
StereoselectivityChemistryEnantiomerStereochemistryEnzymeEnantioselective synthesisMutagenesisBiocatalysisActive siteSubstrate (aquarium)Combinatorial chemistryOptically activeBiochemistryOrganic chemistryCatalysisBiologyMutationGeneEcologyIonic liquidEnzyme Catalysis and ImmobilizationComputational Drug Discovery MethodsPlant biochemistry and biosynthesis