Split Locations and Secondary Structures of a DNAzyme Critical to Binding-Assembled Multicomponent Nucleic Acid Enzymes for Protein Detection
Yiren Cao, Hongquan Zhang, X. Chris Le
Abstract
) provide a new approach to studying other partial (split) DNAzymes and engineering better MNAzymes for the detection of specific proteins.
Topics & Concepts
DeoxyribozymeNucleic acidChemistryRNACleavage (geology)Protein secondary structureDNAThymineCatalysisNucleic acid structureBiochemistryNucleic acid secondary structureEnzymeCombinatorial chemistryBiophysicsStereochemistryBiologyGenePaleontologyFracture (geology)Advanced biosensing and bioanalysis techniquesRNA and protein synthesis mechanismsBacteriophages and microbial interactions