Janus Kinase Inhibition in the Aicardi–Goutières Syndrome
Adeline Vanderver, Laura Adang, Francesco Gavazzi, Katherine McDonald, Guy Helman, David B. Frank, Nicole Jaffe, Sabrina W. Yum, Abigail Collins, Stephanie Keller, Pierre Lebon, Jean–François Méritet, Jullie Rhee, Asako Takanohashi, Thaís Armangué, Nicole Ulrick, Omar Sherbini, Jamie Koh, Kyle Peer, Constance Besnier, Carly Scher, Katherine Boyle, Holly Dubbs, Julia Kramer-Golinkoff, Amy Pizzino, Sarah Woidill, Justine Shults
Abstract
JAK Inhibition in the Aicardi–Goutieres Syndrome Patients with the Aicardi–Goutieres syndrome, an autosomal recessive disorder that affects the central nervous system, immune system, and skin, have...
Topics & Concepts
Janus kinaseCentral nervous systemImmune systemMedicineKinaseInternal medicineGeneticsBiologyImmunologySystemic Lupus Erythematosus Researchinterferon and immune responsesCytokine Signaling Pathways and Interactions