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Effects of Exosomes on Tumor Bioregulation and Diagnosis

Tong Wu, Ying Liu, Nasra Mohamoud Ali, Bin Zhang, Xiaonan Cui

2023ACS Omega15 citationsDOIOpen Access PDF

Abstract

Exosomes are lipid bilayer vesicles in biological fluids, which can participate in biological processes by mediating intercellular communication and activating intracellular signaling pathways, especially cancerogenic processes, such as proliferation, metastasis, invasion, and immune regulation of cancer cells. Besides, cancer-derived exosomes are also involved in tumor diagnosis and therapy as biomarkers and nanotransport devices. This article reviews the latest research progress on the biological regulation and disease diagnosis of exosomes in tumors, with the aim of providing new ideas for the clinical treatment of cancers.

Topics & Concepts

MicrovesiclesImmune systemMetastasisCancer researchIntracellularCancerDiseaseMedicineBiologyCell biologyImmunologymicroRNAPathologyInternal medicineBiochemistryGeneExtracellular vesicles in diseaseMicroRNA in disease regulationCancer-related molecular mechanisms research
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