Intensified antibody response elicited by boost suggests immune memory in individuals administered two doses of SARS-CoV-2 inactivated vaccine
Yun Liao, Ying Zhang, Heng Zhao, Jing Pu, Zhimei Zhao, Dandan Li, Shengtao Fan, Li Yu, Xingli Xu, Li‐Chun Wang, Guorun Jiang, Longding Liu, Qihan Li
Abstract
Neutralizing antibodies in the subjects of an inactivated SARS-CoV-2 vaccine clinical trial showed a decreasing trend over months. An investigation studying the third immunization suggested that the waning of neutralizing antibodies in individuals administered two doses of inactivated vaccine does not mean the disappearance of immunity.
Topics & Concepts
AntibodyImmunizationVirologyMedicineImmunityImmune systemNeutralizing antibodyImmunologyInactivated vaccineAntibody responseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VaccinationCoronavirus disease 2019 (COVID-19)DiseaseInternal medicineInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchVaccine Coverage and HesitancySARS-CoV-2 detection and testing