Synthesis, biological evaluation, and molecular modeling simulations of new heterocyclic hybrids as multi-targeted anti-Alzheimer's agents
Omnia M. Waly, Karim M. Saad, Hussein I. El‐Subbagh, Said M. Bayomi, Mariam A. Ghaly
Topics & Concepts
ChemistryTacrineNeurotoxicitySynthonCombinatorial chemistrySmall moleculeAmideLead compoundStereochemistryStructure–activity relationshipIn vitroBiochemistryToxicityOrganic chemistryAcetylcholinesteraseEnzymeCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsSynthesis and biological activity