A modular olefination reaction between aldehydes and diborylsilylmethide lithium salts
Oriol Salvadó, Elena Fernández
Abstract
We describe the preparation of densely functionalised 1,1-silylborylated trisubstituted alkenes, via a boron-Wittig reaction, between LiC(Bpin)2(SiMe3) and aliphatic or aromatic aldehydes. The condensation of diborylsilylmethide lithium salts with α,β-unsaturated aldehydes provides a direct pathway to synthesize 1,1-silylborylated conjugated dienes and diynes.
Topics & Concepts
Lithium (medication)ChemistryModular designOrganic chemistrySalt (chemistry)Combinatorial chemistryComputer scienceBiologyEndocrinologyOperating systemOrganoboron and organosilicon chemistryCoordination Chemistry and OrganometallicsSynthesis and characterization of novel inorganic/organometallic compounds